Giacomello Lab

Welcome to Giacomello Lab

Our research group focuses on the fundamental question of how cell localization influences biological processes across different kingdoms and aims to provide clear contributions to the sustainable development goals of the United Nations. 

Our knowledge is multidisciplinary and unified by the study of spatial gene expression dynamics through the development and application of single-cell and spatial transcriptomics approaches, which are core technologies of our lab.

The core values of our lab are being committed to scientific reproducibility and open science. In addition, and with great emphasis, the lab stands firm against academic bullying and to promote mental health in academia.

Current Projects


The plasticity of the mouse heart and brain under microgravity. The final aim is to understand the overall impact of spaceflight at the system level, thus allowing for  improvements in spaceflight conditions for astronauts and to study how extreme stressors affect the human body. The work is conducted in collaboration with NASA (GeneLab).


The reproductive molecular dynamics of Norway spruce to promote faster reforestation processes. We are working in collaboration with the Swedish University of Agricultural Sciences (SLU) to understand key differences between the wildtype (25-30 years to reproduction) and the naturally occurring mutant acrocona (3-5 years to reproduction). 

Group Members

We are a diverse group with members from inter-disciplinary backgrounds: biotechnology, bioinformatics to name a few.